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For the HCP 500 Release, unprocessed and processed data for a subject can be accessed via REST calls.
In order to access data for a subject, you will need to register at https://db.humanconnectome.org
To get data via REST, in a script, you could use tools like curl.
Data organization
100307_CREST/RESOURCES/100307_CREST
unprocessed
3T
T1w_MPR1
All unprocessed files associated with the T1w 3T acquisition
rfMRI_REST2_LR
All unprocessed files associated with the rfMRI_REST2_LR 3T acquisition
tfMRI_GAMBLING_LR
All unprocessed files associated with the tfMRI_GAMBLING_LR 3T acquisition
USAGE
To download a particular file, say T1wthe for a subject, say 100307, you could invoke curl as:
curl -u DB_LOGIN_ID_HERE:DB_PASSWORD_HERE -X GET
https://db.humanconnectome.org/data/archive/projects/HCP_500/subjects/100307/experiments/100307_CREST/resources/100307_CREST/files/T1w/T1w1_gdc.nii.gz